Top 25 College Hoops Picks Against the Spread – Tuesday, February 25

Published 12:28 am Tuesday, February 25, 2025

There are nine games featuring a ranked team on the Tuesday college basketball schedule, including the Mississippi State Bulldogs versus the Alabama Crimson Tide. If you’re seeking against-the-spread picks for each matchup, continue scrolling.

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AP Top 25 Picks ATS Today

Miami Hurricanes vs. No. 2 Duke Blue Devils

Spread Prediction

  • Computer Prediction: Duke 85, Miami (FL) 64
  • Projected Favorite: Duke by 21.4 points
  • Pick ATS: Miami (FL) (+22.5)

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Bet on the Miami (FL)-Duke spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 7 p.m. ET
  • Location: Coral Gables, Florida
  • Venue: Watsco Center
  • TV Channel: ESPN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 21 Marquette Golden Eagles vs. Providence Friars

Spread Prediction

  • Computer Prediction: Marquette 78, Providence 66
  • Projected Favorite: Marquette by 11.9 points
  • Pick ATS: Providence (+12.5)

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Key Facts

  • Time: 7 p.m. ET
  • Location: Milwaukee, Wisconsin
  • Venue: Fiserv Forum
  • TV Channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Georgia Bulldogs vs. No. 3 Florida Gators

Spread Prediction

  • Computer Prediction: Florida 77, Georgia 70
  • Projected Favorite: Florida by 6.3 points
  • Pick ATS: Georgia (+7.5)

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Key Facts

  • Time: 7 p.m. ET
  • Location: Athens, Georgia
  • Venue: Stegeman Coliseum
  • TV Channel: SEC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Oklahoma State Cowboys vs. No. 9 Iowa State Cyclones

Spread Prediction

  • Computer Prediction: Iowa State 80, Oklahoma State 69
  • Projected Favorite: Iowa State by 11.4 points
  • Pick ATS: Iowa State (-10.5)

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Key Facts

  • Time: 8 p.m. ET
  • Location: Stillwater, Oklahoma
  • Venue: Gallagher-Iba Arena
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

No. 14 Missouri Tigers vs. South Carolina Gamecocks

Spread Prediction

  • Computer Prediction: Missouri 81, South Carolina 67
  • Projected Favorite: Missouri by 13.5 points
  • Pick ATS: Missouri (-13.5)

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Key Facts

  • Time: 9 p.m. ET
  • Location: Columbia, Missouri
  • Venue: Mizzou Arena
  • TV Channel: ESPNU
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

Virginia Tech Hokies vs. No. 19 Louisville Cardinals

Spread Prediction

  • Computer Prediction: Louisville 78, Virginia Tech 67
  • Projected Favorite: Louisville by 11.1 points
  • Pick ATS: Louisville (-10.5)

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Key Facts

  • Time: 9 p.m. ET
  • Location: Blacksburg, Virginia
  • Venue: Cassell Coliseum
  • TV Channel: ACC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 11 Wisconsin Badgers vs. Washington Huskies

Spread Prediction

  • Computer Prediction: Wisconsin 82, Washington 68
  • Projected Favorite: Wisconsin by 13.6 points
  • Pick ATS: Washington (+15.5)

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Key Facts

  • Time: 9 p.m. ET
  • Location: Madison, Wisconsin
  • Venue: Kohl Center
  • TV Channel: Peacock
  • Live Stream: Peacock

LSU Tigers vs. No. 5 Tennessee Volunteers

Spread Prediction

  • Computer Prediction: Tennessee 76, LSU 66
  • Projected Favorite: Tennessee by 9.6 points
  • Pick ATS: LSU (+10.5)

Bet on the LSU-Tennessee spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 9 p.m. ET
  • Location: Baton Rouge, Louisiana
  • Venue: Pete Maravich Assembly Center
  • TV Channel: SEC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 6 Alabama Crimson Tide vs. No. 24 Mississippi State Bulldogs

Spread Prediction

  • Computer Prediction: Alabama 86, Mississippi State 75
  • Projected Favorite: Alabama by 10.2 points
  • Pick ATS: Alabama (-7.5)

Bet on the Alabama-Mississippi State spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 9 p.m. ET
  • Location: Tuscaloosa, Alabama
  • Venue: Coleman Coliseum
  • TV Channel: ESPN2
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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